Figure 2. The frequency distributions of the five parameters of the metabolic syndrome amongst the participants were as follows: Receive exclusive offers and updates from Oxford Academic. P -value.
Relationship of sex hormone-binding globulin to lipid, lipoprotein, glucose, and insulin concentrations in postmenopausal women. Recent studies have shown that a substantial proportion of the SHBG produced by these cells is retained within them and that this markedly accentuates the androgen-dependent regulation of genes, especially under conditions of androgen withdrawal [ ].
Another limitation to these types of studies is that tissue samples are invariably contaminated by plasma SHBG in their capillary beds, and there is no guarantee that SHBG from plasma sources does not nonspecifically associate with isolated cell types.
Cancer Epidemiol Biomarkers Prev ; 14 : Open in new tab Download slide. This article has been cited by other articles in PMC. La Vignera, R. J Clin Endocrinol Metab ; 63 : SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density.
Received Aug 24; Accepted Feb Low sex hormone binding globulin is a potential marker for the metabolic syndrome in different ethnic groups. Associations among sex hormone binding globulin concentrations and characteristics of the metabolic syndrome in obese women.
J Clin Invest ; 58 : Clin Endocrinol Oxf ; 18 : Mol Cell Endocrinol ; : 21